What are possible harmful side effects of Creatine?
You must drink plenty of water along with the adoption of creatine from 6 to 8 glasses a day.
Although there are not hard evidence possible side effects of its use are dehydration, diarrhea, muscle cramps (involuntary spasms or contractions your muscles), reduced blood volume and electrolyte imbalance in your body. Bigger part of the creatine-monohydrate, pyruvate, and even part of the phosphate is converted into creatine (toxic product) in the process of assimilation and transport to muscle cells. Large percent of this becomes in the cells, immediately before the entry of fuel into mitochondria. The water is needed to do well with toxic effects, the cells increase their volume keeping water. So they actively synthesize “waste bubbles” in which they store the “rubbish”.
You should stop the intake of creatine and to consult a doctor if you notice:
- Allergic reactions (difficulty breathing, dry tongue, lips and throat)
- Symptoms of kidney problems, decreased amount of urine.
What is the way of creatine absorbing by the body and how it comes to the muscles?
Our body absorbs the creatine in small intestine and bloodstream gradually transfers it to the liver. From there it again passes into the bloodstream, and so it reaches to different tissues including muscles and the brain. Then it enters in cells through carrier proteins. It is possible taking creatine for long time to reduce the number of carrier proteins, and it is unclear whether this process is reversible.
How creatine is producing \ isolating
In industrial scale Creatine is produced by chemical synthesis of two starting substances – from cyanamide or from thiourea. Creatine produced by thiourea contains different impurities – dihydrotriazine, dicyanamide, thiourea residues. Therefore, if it is taken for longer periods can have harmful effects on the body, and it can cause allergies, disturbances in kidney function and cancer.
How you can avoid these harmful effects?
Taking in long period creatine also can injure and even stop your own produce of creatine. If you take creatine this should not continue more than 2 or 3 months. Then you must take a break at least a month. That will stimulate your body to not stop producing.
Creatine is a very important amino acid, but you do not have to take it as a supplement. Human body produces it alone, and although it is too small this natural creatine does not cause harmful side effects. For the body is possible to produce creatine when there are present these amino acids: arginine, glycine and methionine (which are in abundance in fish and red meat).
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